Cell cycle Start is coupled to entry into the yeast metabolic cycle across diverse strains and growth rates.
Molecular biology of the cell (2016)
Role of DNA binding sites and slow unbinding kinetics in titration-based oscillators
Physical Review E (2015)
The Physarum polycephalum Genome Reveals Extensive Use of Prokaryotic Two-component and Metazoan-type Tyrosine Kinase Signaling.
Genome biology and evolution (2015)
Different Mechanisms Confer Gradual Control and Memory at Nutrient- and Stress-Regulated Genes in Yeast.
Molecular and cellular biology (2015)
Redox rhythm reinforces the circadian clock to gate immune response.
Redox rhythm reinforces the circadian clock to gate immune response
Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy.
Molecular biology of the cell (2014)
Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy
Molecular Biology of the Cell (2014)
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Our lab is interested in the systems biology and evolution of epigenetic switches (bistability) and clocks (oscillators) in gene regulatory networks, two functions that are essential for patterning, cell proliferation, and differentiation in biological systems. We also study biochemical oscillators such as the cell cycle, metabolic rhythms, and circadian clocks, which co-exist in the same cells and interact with one another through shared resources.
M.S. - University of Michigan at Ann Arbor
B.S. - University of California at San Diego