On schemes of combinatorial transcription logic.
Proc Natl Acad Sci U S A (2003)
Surveying determinants of protein structure designability across different energy models and amino-acid alphabets: A consensus
J. Chem. Phys. (2000)
Universal correlation between energy gap and foldability for the random energy model and lattice proteins
J. Chem. Phys. (1999)
Effect of alphabet size and foldability requirements on protein structure designability.
Protein heteronuclear NMR assignments using mean-field simulated annealing.
J Magn Reson (1997)
BL Herculis model pulsations; III. Livermore opacities
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Bistable and oscillatory dynamics in regulatory networks are essential for patterning, cell proliferation, and cell differentiation in biological systems. My lab takes an interdisciplinary approach (theory and experiment; physics and biology; synthetic and systems biology) to understand the diverse molecular and evolutionary mechanisms by which thresholds, combinatorial control, bistability, and oscillation have evolved in biological systems.
BS - University of California, San Diego