Bastiaan Driehuys

Associate Research Professor

Office: 
161-B Bryan Research, 311 Research Drive, Durham, NC 27710
Campus Box: 
3302 Med Ctr
Phone: 
(919) 684-7786
Fax: 
(919) 684-7122

Details

Enabling hyperpolarized 129Xe MR spectroscopy and imaging of pulmonary gas transfer to the red blood cells in transgenic mice expressing human hemoglobin
Magnetic Resonance in Medicine (2013)

Quantitative analysis of hyperpolarized 129Xe ventilation imaging in healthy volunteers and subjects with chronic obstructive pulmonary disease
NMR in Biomedicine (2013)

Chronic obstructive pulmonary disease: safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients.
Radiology (2012)

Small animal imaging with magnetic resonance microscopy
ILAR Journal (2012)

Relaxation of hyperpolarized 129Xe in a deflating polymer bag.
Journal of magnetic resonance (San Diego, Calif. : 1997) (2011)

My research program is focused on developing and applying hyperpolarized gases to enable fundamentally new applications in MRI. Currently we use this technology to non-invasively image pulmonary function in 3D. Hyperpolarization involves aligning nuclei to a high degree to enhance their MRI signal by 5-6 orders of magnitude. Thus, despite the low density of gases relative to water (the ordinary signal source in MRI), they can be imaged at high-resolution in a single breath. This technology leads to a host of interesting areas of study including: investigating the basic physics of hyperpolarization, developing new MR methods and hardware for image acquisition, image analysis and quantification, and of, course applying this technology to a host of chronic diseases including, asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis.

Education:
Ph.D. - Princeton University